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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Odor, Taste, and Light Receptors in Unusual Locations

Odor, Taste, and Light Receptors in Unusual Locations

By | September 1, 2016

From the gut and airways to the blood, muscle, and skin, diverse sensory receptors are doing unconventional things.

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image: Proprioception: The Sense Within

Proprioception: The Sense Within

By and | September 1, 2016

Knowing where our bodies are in space is critical for the control of our movements and for our sense of self.

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image: Protein or Perish

Protein or Perish

By | September 1, 2016

A bacteriophage must evolve certain variants of a protein or die.

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image: What Sensory Receptors Do Outside of Sense Organs

What Sensory Receptors Do Outside of Sense Organs

By | September 1, 2016

Odor, taste, and light receptors are present in many different parts of the body, and they have surprisingly diverse functions.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Antibiotic Resistance Reaches Brazil

Antibiotic Resistance Reaches Brazil

By | August 8, 2016

Scientists detect a colistin-resistance gene in a clinical sample.

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image: Fecal Transplant Pill Fails Trial

Fecal Transplant Pill Fails Trial

By | August 1, 2016

Seres Therapeutics’s microbiome-targeting therapy for recurrent Clostridium difficile infection fails a Phase 2 clinical trial.

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From sequencing bacteriophages to synthesizing bacterial genomes to defining a minimal genome

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