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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: What Sensory Receptors Do Outside of Sense Organs

What Sensory Receptors Do Outside of Sense Organs

By | September 1, 2016

Odor, taste, and light receptors are present in many different parts of the body, and they have surprisingly diverse functions.

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image: Popular Tumor Cell Line Contaminated

Popular Tumor Cell Line Contaminated

By | August 31, 2016

A commercially available glioblastoma cell line appears to be from a different source than its stated origins.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Book Excerpt from <em>Seven Skeletons</em>

Book Excerpt from Seven Skeletons

By | August 1, 2016

In Chapter 1, “The Old Man of La Chapelle: The Patriarch of Paleo,” author Lydia Pyne explains the public's evolving conception of the first complete Neanderthal skeleton found and described by scientists.

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By ditching traditional agar-based media, two biochemists captured iconic images of Myxococcus in 1982.

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image: Macrophages Respond to Liver Injury

Macrophages Respond to Liver Injury

By | August 1, 2016

In mice, immune cells from the body cavity surrounding organs arrive at the site of damage to chew up the nuclei of dead cells.

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image: Nailing Down HAR Function

Nailing Down HAR Function

By | August 1, 2016

A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.

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image: Newly Discovered Emergency Responders to Liver Damage

Newly Discovered Emergency Responders to Liver Damage

By | August 1, 2016

Immune cells called macrophages from the peritoneal cavity of mice migrate to injured livers and aid in repair.

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