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tag induced pluripotent stem cell cell molecular biology

A graphic of two stem cells colored pink and blue splitting from each other, with binary code shown in the background.
Fixing the Problem With Induced Pluripotent Stem Cells
Tanvir Khan, PhD | Oct 31, 2023 | 4 min read
A new strategy prevents reprogramming-induced epigenetic aberrations in human induced pluripotent stem cells.
Stem Cells Induced for Conservation
Kerry Grens | Sep 4, 2011 | 2 min read
Researchers generate pluripotent stem cells from two endangered species in hopes of learning more about the near-extinct animals.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Inducing Pluripotency Every Time
Ed Yong | Sep 18, 2013 | 3 min read
By removing a single gene, adult cells can be reprogrammed into a stem-like state with nearly 100 percent efficiency.
Synthego Launches High Throughput Induced Pluripotent Stem Cell Genome Engineering
Synthego | Oct 29, 2019 | 2 min read
National Institutes of Health awards contract for CRISPR-based disease modeling in iPS cell lines associated with Alzheimer’s, Stem cell pioneer Bill Skarnes joins advisory board
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Stem Cell Similarities
Karen Zusi | Oct 28, 2015 | 2 min read
Human induced pluripotent stem cells appear functionally equivalent to stem cells from embryos in a study.
Biology’s New Supermodel
Megan Scudellari | Jul 20, 2011 | 5 min read
Induced pluripotent stem cells are biology’s hottest new tool for understanding human disease.
Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.
Stem Cell Lines Riddled With Undetected Mutations
Dan Robitzski | Aug 12, 2022 | 4 min read
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.
Using CRISPR to Edit Genes in Induced Pluripotent Stem Cells
Kelly Rae Chi | Sep 1, 2016 | 8 min read
Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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