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tag induced pluripotent stem cell developmental biology genetics genomics immunology

Synthego Launches High Throughput Induced Pluripotent Stem Cell Genome Engineering
Synthego | Oct 29, 2019 | 2 min read
National Institutes of Health awards contract for CRISPR-based disease modeling in iPS cell lines associated with Alzheimer’s, Stem cell pioneer Bill Skarnes joins advisory board
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016 | 6 min read
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Pluripotency: the third option?
Elie Dolgin | Jun 15, 2009 | 4 min read
The excitement surrounding cellular reprogramming and the possibility of federal funding for human embryonic stem cell (ESC) research in the US could be overshadowing another promising therapeutic source of stem cells: those derived via parthenogenesis, some researchers say. But later-developed techniques such as induced pluripotent stem cells (iPSCs) could make this approach obsolete, and the final draft of the stem cell guidelines, due out by July 7, might put the nail in the parthenote coffin
Study: MicroRNA, Retroviruses Coordinate to Influence Pluripotency
Joshua A. Krisch | Jan 13, 2017 | 2 min read
Removing a specific miRNA from stem cells may induce the expression of endogenous retroviruses that enable the cells to form extra-embryonic lineages.
Top 7 in developmental biology
Bob Grant | Dec 17, 2010 | 3 min read
A snapshot of the most highly ranked articles in developmental biology, from Faculty of 1000
Skipping Pluripotency
Jef Akst | Sep 14, 2011 | 5 min read
Researchers are developing ways to convert mature somatic cells from one cell type to another, avoiding the tumor-causing pluripotent stage associated with stem cells.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

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