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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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Disrupting the light/dark cycles of pregnant mice, researchers observe detrimental effects in the mouths of the animals’ pups.

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image: Nailing Down HAR Function

Nailing Down HAR Function

By | August 1, 2016

A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.

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image: Plastic Pollutants Can Harm Fish

Plastic Pollutants Can Harm Fish

By | June 6, 2016

European perch larvae exposed to environmentally relevant concentrations of polystyrene particles preferred to eat the microplastics in place of prey, according to a study.

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image: Research at Micro- and Nanoscales

Research at Micro- and Nanoscales

By | June 1, 2016

From whole cells to genes, closer examination continues to surprise.  

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image: Editing Genomes to Record Cellular Histories

Editing Genomes to Record Cellular Histories

By | May 26, 2016

Researchers harness the power of genome editing to track cell lineages throughout zebrafish development.

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image: Embryo Watch

Embryo Watch

By | May 5, 2016

A new culture system allows researchers to track the development of human embryos in vitro for nearly two weeks.

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image: Cellular Pruning Follows Adult Neurogenesis

Cellular Pruning Follows Adult Neurogenesis

By | May 2, 2016

Newly formed neurons in the adult mouse brain oversprout and get cut back.

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image: A Gut Feeling

A Gut Feeling

By | April 1, 2016

See profilee Hans Clevers discuss his work with stem cells and cancer in the small intestine.

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image: Guts and Glory

Guts and Glory

By | April 1, 2016

An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

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