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image: Regulators OK Clinical Trials Using Donor Stem Cells

Regulators OK Clinical Trials Using Donor Stem Cells

By | February 6, 2017

Japanese health officials approve human experiments to treat macular degeneration with a cell therapy derived from induced pluripotent stem cells.

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Removing a specific miRNA from stem cells may induce the expression of endogenous retroviruses that enable the cells to form extra-embryonic lineages.

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image: Donor Stem Cells Improve Cardiac Function

Donor Stem Cells Improve Cardiac Function

By | October 12, 2016

After a heart attack, monkeys given induced pluripotent stem cell–derived cardiomyocytes show more regeneration in the organ, but with risks.

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image: Stem Cells Made Waves in Biology and Medicine

Stem Cells Made Waves in Biology and Medicine

By | October 1, 2016

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

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image: Thirty Years of Progress

Thirty Years of Progress

By | October 1, 2016

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Nailing Down HAR Function

Nailing Down HAR Function

By | August 1, 2016

A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.

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image: Putting the Pee in Pluripotency

Putting the Pee in Pluripotency

By | April 1, 2016

One man’s waste is another man’s treasure trove of stem cells.

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image: CRISPRi-Controlled Gene Expression

CRISPRi-Controlled Gene Expression

By | March 10, 2016

A variation of the gene-editing technique can more precisely and efficiently downregulate the expression of target genes than traditional CRISPR/Cas9.

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image: Mice Develop with Human Stem Cells

Mice Develop with Human Stem Cells

By | December 21, 2015

Human embryonic stem cells and induced pluripotent stem cells participated normally in early mouse embryo development in a recent study.

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