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Researchers are using CRISPR for precise genetic manipulation of human-associated microbes as a promising avenue for improving human health.

Multi-targeted Cas13 screens help researchers avoid permanent DNA cuts and evade T cell exhaustion.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.

Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.

A CRISPR-based screening platform helped scientists identify a transcription factor that makes CAR T cells better at killing cancer cells. 

CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.