A lot of bloody genes

In the 2 June Science, Phillips et al announce the creation of the Stem Cell Database (SCDb), an annotated collection of genes expressed in hematopoietic stem cells (Science 2000, 288:1635-1640). Most of the data are based on the sequencing of 5735 clones from a subtracted stem cell library, representing at least half of the library's complexity. The SCDb reveals clues to stem cell biology, such as the coincidence of semaphorins and their ligands, suggesting that these molecules are important fo

By | June 7, 2000

In the 2 June Science, Phillips et al announce the creation of the Stem Cell Database (SCDb), an annotated collection of genes expressed in hematopoietic stem cells (Science 2000, 288:1635-1640). Most of the data are based on the sequencing of 5735 clones from a subtracted stem cell library, representing at least half of the library's complexity. The SCDb reveals clues to stem cell biology, such as the coincidence of semaphorins and their ligands, suggesting that these molecules are important for stem cell adhesion and homing. But, perhaps most importantly, the list of genes will serve as the basis for stem cell microarrays that can be used to analyze changes in regulatory networks as stem cells renew and differentiate.

Popular Now

  1. How Plants Evolved Different Ways to Make Caffeine
  2. Thomson Reuters Predicts Nobelists
    The Nutshell Thomson Reuters Predicts Nobelists

    According to citation statistics, researchers behind programmed cell death pathways and CRISPR/Cas9 are among those in line for Nobel Prizes this year.

  3. Sequencing Reveals Genomic Diversity of the Human Brain
  4. Reviewing Results-Free Manuscripts
    The Nutshell Reviewing Results-Free Manuscripts

    An open-access journal is trialing a peer-review process in which reviewers do not have access to the results or discussion sections of submitted papers.

RayBiotech