Advertisement
NorthEastern
NorthEastern

Metformin and lipodystrophy

NEW YORK, 26 July (Praxis Press) The human immunodeficiency virus (HIV) lipodystrophy syndrome is characterized by fat redistribution and insulin resistance; this syndrome is particularly common among patients receiving combined antiretroviral therapy. Hadigan and colleagues studied the safety and efficacy of metformin in patients with the HIV lipodystrophy syndrome. Low-dose metformin treatment decreased body mass index and abdominal fat, improved hyperinsulinemia, and lowered diastolic blood p

July 27, 2000

NEW YORK, 26 July (Praxis Press) The human immunodeficiency virus (HIV) lipodystrophy syndrome is characterized by fat redistribution and insulin resistance; this syndrome is particularly common among patients receiving combined antiretroviral therapy. Hadigan and colleagues studied the safety and efficacy of metformin in patients with the HIV lipodystrophy syndrome. Low-dose metformin treatment decreased body mass index and abdominal fat, improved hyperinsulinemia, and lowered diastolic blood pressure. No serious adverse effects were noted; mild diarrhea was the most common minor adverse effect. Low-dose metformin is an effective and well-tolerated treatment for HIV lipodystrophy.

Advertisement
QIAGEN ingenuity
QIAGEN ingenuity

Popular Now

  1. The Zombie Literature
    Features The Zombie Literature

    Retractions are on the rise. But reams of flawed research papers persist in the scientific literature. Is it time to change the way papers are published?

  2. First Data from Anti-Aging Gene Therapy
  3. Locating Language within the Brain
  4. A Scrambled Mess
    Features A Scrambled Mess

    Why do so many human eggs have the wrong number of chromosomes?

Advertisement
SomaLogic
SomaLogic
Advertisement
LabX
LabX
RayBioTech