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Diabetes and exercise

NEW YORK, July 26 (Praxis Press) Regular physical activity is independently associated with a reduction in the risk of major coronary heart disease (CHD) events and type 2 diabetes. However, few prospective studies have investigated the role of insulin as a mediating factor in the relationship between physical activity and CHD or type 2 diabetes. To examine this relationship, Wannamethee and colleagues performed a prospective study of 5,159 men aged 40 to 59 years with no history of CHD, type 2

July 31, 2000

NEW YORK, July 26 (Praxis Press) Regular physical activity is independently associated with a reduction in the risk of major coronary heart disease (CHD) events and type 2 diabetes. However, few prospective studies have investigated the role of insulin as a mediating factor in the relationship between physical activity and CHD or type 2 diabetes. To examine this relationship, Wannamethee and colleagues performed a prospective study of 5,159 men aged 40 to 59 years with no history of CHD, type 2 diabetes, or stroke and measured various physical, biochemical and hematological variables in these men. During an average follow-up period of 16.8 years, there were 616 cases of major CHD events (fatal and nonfatal) and 196 incident cases of type 2 diabetes. They found that the relationship between physical activity and type 2 diabetes appeared to be mediated by serum true insulin level and components of the insulin resistance syndrome but these factors did not explain the inverse relationship between physical activity and coronary heart disease.

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