Advertisement

Pravastatin and stroke

Pravastatin may lower stroke risk in patients with coronary artery disease.

August 8, 2000

NEW YORK, August 3 (Praxis Press) The role of cholesterol-lowering therapy in reducing the risk of stroke is unknown and several epidemiological studies have concluded that there is no relation between total cholesterol levels and the risk of stroke. To study this relationship further, White and colleagues examined 9,014 patients with coronary artery disease and randomly assigned them to receive either pravastatin or a placebo. During a mean follow-up period of 6 years, 3.7% of the patients taking pravastatin had a stroke, compared with 4.5% of patients taking a placebo—a 19% reduction in the overall risk of stroke. Nonhemorrhagic stroke occurred in 3.5% of the patients taking pravastatin as compared with 4.4% of the patients taking placebo. Pravastatin has a moderate effect in reducing the risk of stroke in patients with previous myocardial infarction or unstable angina.

Advertisement
The Scientist
The Scientist

Follow The Scientist

icon-facebook icon-linkedin icon-twitter icon-vimeo icon-youtube

Stay Connected with The Scientist

  • icon-facebook The Scientist Magazine
  • icon-facebook The Scientist Careers
  • icon-facebook Neuroscience Research Techniques
  • icon-facebook Genetic Research Techniques
  • icon-facebook Cell Culture Techniques
  • icon-facebook Microbiology and Immunology
  • icon-facebook Cancer Research and Technology
  • icon-facebook Stem Cell and Regenerative Science
Advertisement
Synthetic Genomics
Synthetic Genomics
Advertisement
Life Technologies