Advertisement
NorthEastern
NorthEastern

A sea urchin genome project

Sea urchins are popular in developmental biology research thanks to their well defined embryology, the ease of gene transfer into eggs, and the abundance of eggs for biochemical work. Now the sea urchin genome project is off to a start with sequence from the ends of 76,020 bacterial artificial chromosome (BAC) recombinants. In the August 15 Proceedings of the National Academy of Sciences, Cameron et al. report that these sequence tag connectors (STCs) occur at an average of 10 kb apart in the s

By | August 17, 2000

Sea urchins are popular in developmental biology research thanks to their well defined embryology, the ease of gene transfer into eggs, and the abundance of eggs for biochemical work. Now the sea urchin genome project is off to a start with sequence from the ends of 76,020 bacterial artificial chromosome (BAC) recombinants. In the August 15 Proceedings of the National Academy of Sciences, Cameron et al. report that these sequence tag connectors (STCs) occur at an average of 10 kb apart in the sea urchin genome and provide sequence of >5% of the genome (Proc Natl Acad Sci USA 2000, 97:9514-9518). The collaborating groups have also produced cDNA libraries of >105 clones for every major stage of embryogenesis, and are in the process of producing the complete sequence of the 500 kb Hox gene complex.

Popular Now

  1. The Zombie Literature
    Features The Zombie Literature

    Retractions are on the rise. But reams of flawed research papers persist in the scientific literature. Is it time to change the way papers are published?

  2. First Data from Anti-Aging Gene Therapy
  3. Locating Language within the Brain
  4. The Two Faces of Fish Oil
    Notebook The Two Faces of Fish Oil

    The discovery of a tumor-protecting role for a fatty acid found in fish oil has sparked debate about the product’s safety.

Advertisement
Advertisement
LabX
LabX
RayBioTech