Male flies compensate for having a single X chromosome by doubling the single X chromosome's level of expression. This increase is mediated by MOF, a histone H4 acetyltransferase. MOF, along with other proteins and an RNA called roX2, binds to the male X chromosome. In the 21 September
Infected with Wolbachia, the insects are expected to reduce the spread of dengue and Zika. But scientists say the approach may have limitations.