The findings of a recent study suggest that air travel does not increase the risk of deep-vein thrombosis (DVT), challenging the widely held view that DVT is one of the most common conditions associated with air travel. In the study, published as a short Research Letter in the 28 October
Similar proportions of patients with DVT (2.15%) and without DVT (2.16%) reported a history of air travel during the preceding 4 weeks. Air travel alone was not associated with an increased risk of DVT (odds ratio, 1.0; 95% confidence interval, 0.3—1.4); furthermore, travel using any form of transportation (plane, car, bus, train, and boat combined) was not associated with an increased risk of DVT (odds ratio, 0.7; 95% confidence interval, 0.3–1.4). The data also refuted any association between prolonged travel (more than 5 hours) and DVT (odds ratio, 0.4; 95% confidence interval, 0.1–1.3). The findings were similar when patients younger than 65 years were analyzed separately (odds ratio, 1.0; 95% confidence interval, 0.4–2.2). The authors conclude that air travel, even prolonged air travel, is not associated with an increased risk of DVT.