A study on microbe versus microbe battles within the human nose yields a new antibiotic.
The Bacillus subtilis SpoIIIE protein is required for DNA segregation during the asymmetric cell division that produces a mother cell and a pre-spore. In the 3 November Science, Bath et al. confirm that SpoIIIE is targeted to the leading edge of the septum that divides the two cells, and suggest that the protein pumps DNA into the pre-spore by tracking along DNA (Science 2000, 290:995-997). They find that SpoIIIE is a DNA-dependent ATPase that can introduce unconstrained supercoils into a DNA su
November 9, 2000|