Advertisement
LabX
LabX

Slimy catenins

A slime mold, like metazoans, has a beta-catenin involved both in signaling and in forming adherens junctions.

By | December 11, 2000

In the 7 December Nature Grimson et al. report that, like metazoans, the slime mold Dictyostelium discoideum has a β-catenin involved both in signaling and in forming adherens junctions (Nature 2000, 408:727-731). The junctions form after the unicellular amoebae are starved and aggregate into a fruiting body, with junctions present only between cells at a constriction near the top of the stalk tube. In mutants lacking the β-catenin, most of the fruiting bodies collapse, and there is an additional signaling defect: a cell-autonomous failure to induce certain aspects of prespore gene expression. The existence of the Dictyostelium protein and a related protein in the plant Arabidopsis thaliana suggest that evolution of β-catenin may have been a prerequisite for all multicellular development.

Advertisement
QIAGEN ingenuity
QIAGEN ingenuity

Popular Now

  1. LabQuiz: What's Your Cell IQ?
    Sponsored Quiz LabQuiz: What's Your Cell IQ?

    Your body is made up of trillions of cells—but what do you really know about them? Take our lab quiz and determine your CIQ (cell identification quotient). 

  2. Genetic Connections Among Human Traits
  3. Antibiotics From Scratch
  4. Further Evidence that Life Might Have Started with RNA
Advertisement
LabX
LabX
Advertisement
LabX
LabX
Biosearch Technologies
illumina Corporate
illumina Corporate