C. elegans provides an ideal an attractive model for genetic and biochemical experimentation. Nothing wrong to say that C. elegans is micro-guinea pig for the modern day biological experimentation. It is a multi-cellular animal, yet small, ~ 1mm in length, and transparent throughout its life. It is easy to generate mutations in C. elegans. It is known that most of the endocrine signaling and genetic pathways identified in C. elegans persist with evolution in the more complex organisms including human-being. This article provides an insight into the complexity of genome of this simple multi-cellular organism. A passing interest in science in general and genetics in particular is one thing, but a concrete effort of several years to identify the basics is really commendable.