Edwin Krebs has done so much for the field of protein phosphorylation and cell signaling more than any body I have known since I started working in this area. He also trained tens and even hundreds of scientists who are still carrying his message and follow his early work in pursuing their careers. Furthermore, this man has great passion for science even when he was in his eighties more than I have seen for some in their thirties. Finally, he was eager to expalin to you whatever on his mind on signaling pathways using blackboard that he used to have in his office. He will certainly be missed by all who have known him and will always be remembered as one of the shining stars that will continue to guide scientific discoveries for many years to come even after his passing.