Based on my two-decades-old theory of cell life and my insightful knowledge on development of multicellular lives from single cells, I have pointed out that some embryonic stem cells (ESCs) should live into adulthood and become adult stem cells (ASCs) (See http://im1.biz/Aging.htm ). These indigenous or resident ASCs are responsible for the maintenance of normal structure and function of tissues and can be activated if necessary to achieve regeneration. As a matter of fact, a Chinese surgeon his name is XU Rong-Xiang has used in situ activation of such ASCs he named as regenerative stem cells (RSCs) in his clinical practice.\nHowever, the western world has neglected these discoveries and innovations. Instead, they have gone a wrong way to reach (not yet) the goal of regenerative medicine. They first transformed ASCs and other progenitor cells into so-called induced pluripotent stem cells but really incorrectly programmed stem cells or man-made cancer cells (see http://im1.biz/iPS.htm and http://im1.biz/StemCell.htm ). Then they wish to transplant these transformed cells into a recipient to achieve their desired cell therapy.\nThe demonstration of resident stem cells in lung and their capability of regenerating lung tissue thus has provided a convincing evidence for existence of indigenous ASCs and their role for in situ regeneration. It also indicates that the extra and risky efforts of achieving cell therapy by even transforming normal cells into cancer cells are underserved.