HPV vaccine shows promise

An HPV vaccination program in Australia appears to have resulted in a drop in cervical lesions among young women.

By | June 22, 2011

CDC, JAMES GATHANY

For diseases that are slow to spread and develop, it's not always easy to tell if a vaccine is effective. But just 3 years into an HPV vaccination program in the Australian state of Victoria, young women are showing lower rates of cervical lesions, according to a new study published online last week (June 17) in The Lancet.

After the HPV vaccine was licensed in 2006, Australia became the first country to initiate a national program the following year, delivering as many vaccines as possible to women 12 to 26 years old. The new study is the first to compare the incidence of cervical abnormalities among women and girls before and after the vaccine program began. The results revealed that high-grade cervical abnormalities, such as precancerous cellular changes, were about half as common in girls under the age of 18 after the vaccine was introduced—0.42 percent compared to 0.8 percent. No such effect was found in women over the age of 18, and no changes were seen in either group's frequency of low-grade abnormalities, but those impacts will likely be revealed in time. For now, even though circumstances other than the impact of the vaccine may have played a role in the apparent drop in cervical lesions, the evidence of an effect in younger girls is an impressive, even surprising result at this early stage. "Most models have predicted that we would not see an impact from the vaccine until 7 to 10 years" after its introduction, Mona Saraiya, a preventive medicine and public health physician at the U.S. Centers for Disease Control and Prevention in Atlanta, told ScienceNOW.

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. First In Vivo Function Found for Animal Circular RNA
  2. A Potential Remedy for the Aging Brain
    The Scientist A Potential Remedy for the Aging Brain

    In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease. 

  3. Nature Index Identifies Top Contributors to Innovation
  4. Your Body Is Teeming with Weed Receptors
    Features Your Body Is Teeming with Weed Receptors

    And the same endocannabinoid system that translates marijuana's buzz-inducing compounds into a high plays crucial roles in health and disease outside the brain.

AAAS