Death or Damage of Dopamine Neurons

The hallmark pathology of Parkinson’s disease is the damage and death of dopamine producing neurons in the brain. 

By | February 1, 2011

Infographic: Death or Damage of Dopamine Neurons
View full size JPG | PDF
LUCY READING-IKKANDA

The hallmark pathology of Parkinson’s disease is the damage and death of dopamine producing neurons in the brain. Dopamine plays a role in controlling movement, cognition, learning, and mood, explaining the dementia and difficulty with motor control exhibited by patients with deficits in the production of this key neurotransmitter. The a-synuclein gene was one of the first to be implicated in this disease. It produces a protein that can, in certain circumstances, aggregate to form bundles that are a major component of Lewy bodies—fibers that disrupt normal cell processes. Recently researchers have discovered other mechanisms by which this protein damages or kills dopamine-producing neurons, as well as other genes that may also play a role in driving the disease.

Read the full story.

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. First In Vivo Function Found for Animal Circular RNA
  2. Your Body Is Teeming with Weed Receptors
    Features Your Body Is Teeming with Weed Receptors

    And the same endocannabinoid system that translates marijuana's buzz-inducing compounds into a high plays crucial roles in health and disease outside the brain.

  3. Opinion: We Need a Replacement for Beall’s List
  4. Doctors’ Advice to Finish Antibiotics Overlooks Resistance
AAAS