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Weeding Out Bad Stem Cells

A new antibody cocktail can remove undifferentiated, tumor-forming cells from a mix of embryonic stem cells.

By | August 16, 2011

FLICKR, AJC1

The tendency of embryonic and induced pluripotent stem cells to form teratomas is a major factor hindering their development as human therapies. Intent on developing a way to sift out the tumor-forming, pluripotent cells from a hodgepodge cell culture, researchers have identified a cocktail of three antibodies that specifically bind to undifferentiated cells. Their findings were published this week in Nature Biotechnology.

While two of these antibodies were already commercially available, the researchers generated a third antibody, which they named stage-specific embryonic antigen-5 (SSEA-5), to bind to glycan molecules found only in early embryonic pluripotent cells. Used in conjunction, the three antibodies removed most tumorigenic cells from culture, although the researchers still observed abnormal growth in the resulting cell mix, Science Codex reports.

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Avatar of: Kaddcaa51

Anonymous

August 20, 2011

the people that have this terrible disease Duchane Muscular Dystrophy, Becker, or any other form of MD, needs answers soon, like yesterday, for them,they do not have all the time in the world,  hurry up and give them something NOW, all this millions the MDA has aquired during all these decades of collecting money and still have not come up with a pill, treatment to stop this disease, just promises that do not go anywhere. Other countries have studies going on with stem cells, but not us, too much damn red tape, think about the poor kids that are suffering and parents like us that feel helpless , and do not have the 25,000 to 30,0000 dollas to take the love one to get treated at another countries, maybe it will work or maybe not , but at least it would be a hope, or the potential or working. Damn republicans, hope one of them will get a child with DMD so they can feel what I am feeling right now, hopless.

Avatar of:

Posts: 0

August 20, 2011

the people that have this terrible disease Duchane Muscular Dystrophy, Becker, or any other form of MD, needs answers soon, like yesterday, for them,they do not have all the time in the world,  hurry up and give them something NOW, all this millions the MDA has aquired during all these decades of collecting money and still have not come up with a pill, treatment to stop this disease, just promises that do not go anywhere. Other countries have studies going on with stem cells, but not us, too much damn red tape, think about the poor kids that are suffering and parents like us that feel helpless , and do not have the 25,000 to 30,0000 dollas to take the love one to get treated at another countries, maybe it will work or maybe not , but at least it would be a hope, or the potential or working. Damn republicans, hope one of them will get a child with DMD so they can feel what I am feeling right now, hopless.

Avatar of:

Posts: 0

August 20, 2011

the people that have this terrible disease Duchane Muscular Dystrophy, Becker, or any other form of MD, needs answers soon, like yesterday, for them,they do not have all the time in the world,  hurry up and give them something NOW, all this millions the MDA has aquired during all these decades of collecting money and still have not come up with a pill, treatment to stop this disease, just promises that do not go anywhere. Other countries have studies going on with stem cells, but not us, too much damn red tape, think about the poor kids that are suffering and parents like us that feel helpless , and do not have the 25,000 to 30,0000 dollas to take the love one to get treated at another countries, maybe it will work or maybe not , but at least it would be a hope, or the potential or working. Damn republicans, hope one of them will get a child with DMD so they can feel what I am feeling right now, hopless.

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