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Ingenuity
Ingenuity

Europe Pours $41 Million Into Epigenome

The European Commission takes a major step towards unraveling the secrets of human epigenetics.

By | September 29, 2011

BloodCDC, JANICE HANEY CARR

The European Commission has promised 30 million Euro ($41 million) to fund 41 institutions across Europe to study the epigenome as a part of a project called BLUEPRINT. The EC's project is one arm of the International Epigenome Consortium (IHEC), which was started last year. The IHEC will coordinate the efforts of member agencies from the EU, United States, Japan, and other countries to generate a reference epigenome that can be used in much the same way that the human genome is used by researchers today.

"BLUEPRINT is the first big epigenome project to be specifically created in alignment with the IHEC mission," Peter Jones from the University of Southern California told Nature. The project will focus on generating the epigenomes of 60 different blood cell types from samples in United Kingdom's national blood bank. In addition, they will compare some of the markers across 100 healthy people to look for individual differences.  In addition to looking at healthy individuals, BLUEPRINT researchers will study the epigenomes of blood cancers.

"Blood epigenomes are particularly exciting because we know an awful lot about the biology of how blood stem cells differentiate, but little about the sequence of epigenomic events involved in the processes that are going to be relevant for disease," Jones, who is part of IHEC's scientific steering committee, told Nature.

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Avatar of: dovhenis

dovhenis

Posts: 97

September 29, 2011

Imagine, just imagine, the interest and activity big bang in
science if/when finally freed from AAAS stock !!!

 

Science is not another, AAAS
trade-union peer-reviewed, religion.

It takes continuously  critical
refreshed thinking....

 

 

Whence And Whither

Extend Darwin-Einstein Horizon, EmD

 

 

EmD versus Emc

http://dovhenis.wordpress.com/...

 

E = mc2 relates E and m via constant c.

However, since E and c are constant m
must also be constant…?!

Yet for engineering-technology
applications the equation is practical,  fine.

 

E=Total[m(1 + D)] relates E and m via
the variable D. D is the sum total of distance, in ALL spatial
directions,  travelled by m since start of reconversion of m to E.

This relationship is science, not
engineering or technology. E is constant, m and D are variables. D cannot be
less than zero, and m varies with D. This is universal reality.

 

In this reality there is no missing
E.  E is there, transformed to mD.  mD is E.

In this reality there is no missing m.
 m is there, transformed to mD. mD is E.

 

Think about it. This is the
basis-essence of Evolution, of ALL evolutions. Evolutions are the quantum
mechanics of all processes.

 

 

Dov Henis

(comments from 22nd century)

 

-------------------------------------

 

“how species come to be…â€쳌

 

http://www.sciencenews.org/ind...

http://dovhenis.wordpress.com/...

 

What drives “species come to beâ€쳌 is what drives all
life/organisms to come to be,  i.e.  a proven successful route,
circumstantially evolved culture, that enhanced the RNAs’ constrained energy by
the culturally enhanced  RNAs’ proliferation, followed with accordingly
alternatively spliced expression.

 

This is evolution, i.e. enhanced constrained energy to
delay-postpone the universal conversion of mass-formats to energy, to the
energy that keeps fueling the expansion of the universe. This expansion will be
overcome by gravity upon depletion of the universe’s massfuel, and will be
followed by empansion for accelerating reverting of energy to mass all the way
back to singularity. The universe is an allmass allenergy poles affair.

 

Dov Henis

(comments from 22nd century)

http://dovhenis.wordpress.com/...

 

PS:

- It's culture that modifies genetics, that changes gene's
expression.  NOT vice versa.

- Epigenetics YOK. Alternative splicing is epiDNAtic, not
epigenetic.

- ALL life is RNAs evolution products. RNAs are Earth's
prime organism.

 

DH

 

========================

 

Update Comprehension Of Universe/Life
Evolution, Of RNA/DNA Mismatch-Relationship

http://dovhenis.wordpress.com/...

 

Genome is evolved by-for RNAs, like all
other Earth organisms:

 

THE National Science And Technology
Policy ISSUE In The USA (And Therefore Elsewhere...):

 

 

The early 20th century brief burst of
scientific evolution started expiring 90 years ago, at the birth of the
"scientists" (what does this mean?) trade-union AAAS.  True to
the AAAS trade-union interests the scientific evolution has grown into the
technology-industrial evolution, with evolved counter-enlightenment, greed
culture.

 

Re Science Education, it's about WHAT,
not about HOW, is taught.

"Scientists"
tradeunion-politically-controled "science" cannot be advanced/updated
regardless of education system...

See the C signature link...

 

Unravel Some Of Nature's Complexities,
A + B + C

(adnauseam, ad shown where these
data-based statements are wrong)

 

 

A.

 

UNRAVEL COMPLEXITIES OF GENETICS.

Extend Evolution/Natural Selection
Backward To Genes/Genomes, BOTH ARE ORGANISMS.

 

Again, Correct Some Figments Of Science
Imagination:

 

1. Dark energy and matter YOK.
Per  E=Total[m(1 + D)]  all the energy and matter of the universe are
accounted for.

Adopt space-massdistance concept,
mass-to-energy reconversion. 

 

2. Higgs Particle YOK. Mass forms below
some value of the above D.

 

3. Galactic clusters formed by
conglomeration?

Galactic clusters formed by Big-Bang's
dispersion, evidenced by their Newtonian behaviour including expansion
acceleration.

 

4. The universe expansion is fueled by
the mass-to-enrgy reconversion. Eventually, as expansion will slow down, will
run out of massfuel, gravity will overcome expansion and initiate empansion
back to singularity. The universe is a cyclic array of energy-mass dualism,
between all-energy and all-mass poles, under omnipresent gravity.

 

5. Natural Selection is a trait of
organisms, life?

No. Natural selection is ubiquitous for
ALL mass formats, all spin arrays. It derives from the expansion of the
universe. All mass formats, regardless of size and type, from black holes to
smallest particles, strive to increase their constrained energy in attempt to
postpone their own reconversion to energy, to the energy that fuels cosmic
expansion.

 

6. Life is an enigma?

Life is just another type of mass
array, a self-replicating mass array. Earth life is a replicating RNAs mass. It
has always been and still is an RNA world. ALL Earth's organisms are evolved
RNAs, evolved for maintaining-enhancing Earth's biosphere, for prolonging RNAs
survival.

 

7. Cells are Earth-life's primal
organisms?

NO. Earth's life day one was the day on
which RNA began replicating. RNAs, genes, are ORGANISMS. And so are their
evolved templates, (RNA and DNA) genomes, ORGANISMS, as evidenced by life's
chirality and by life's sleep.

 

8. Circadian Schmircadian sleep origin?

Sleep is inherent for life via the
RNAs, the primal Earth ORGANISMS originated and originally active only under
direct sunlight, in their pre-metabolism genesis era.

 

9. Epigenetics are heritable gene
functions changes not involving changes in DNA sequence?

The "heritable or enduring
changes" are epiDNAtics, not epigenetics. Alternative splicing is not
epigenetics, even if/when not involving alteration of the DNA sequence. Earth
life is an RNA world.

 

10.Genetics drive biology and culture
modifications?

NO. It is culture that modifies
genetics, not genetics that modifies culture. Culture modifies genetics simply
via the evolutionary natural selection process of the RNA ORGANISMS. Likewise
many natural genetic changes are due to aging and/or circumstantial effects on
the genes and/or genomes ORGANISMS, similar to aging and/or evolutionary
processes in monocell communities or in multicelled organisms.

 

 

SCIENCE SHOULD UNFREEZE. SCIENCE SHOULD
ADJUST ITS VISION, COMPREHENSION AND CONCEPTS.

 

 

Dov Henis

(Comments From 22nd Century)

 

Seed of Human-Chimp Genomes Diversity

http://dovhenis.wordpress.com/...

03.2010 Updated Life Manifest

http://dovhenis.wordpress.com/...

Evolution, Natural Selection, Derive
From Cosmic Expansion

http://darwiniana.com/2010/09/...

Rethink Evolution/Natural Selection

http://darwiniana.com/2011/03/...

 

==========================

 

B.

 

Quantum Mechanics Of Life

Life's Evolution Is The Quantum
Mechanics Of Biology

http://pulse.yahoo.com/_2SF3CJ...

 

From "Essence Of Quantum
Mechanics"

http://pulse.yahoo.com/_2SF3CJ...

 

The universe, and life within it, are
not just conglomerations of mechanisms. The universe, and life within it, have
come into being by the nature of energy-mass dualism, and their fate, their
final outcome, is governed by this dualism. The genesis and, most probable
cyclic, existence of the universe are governed by the energy-mass relationship.

 

Energy-mass relationship governs also
the routes, the mechanisms, of cosmic and life evolutions.

 

Mechanisms do not set/determine the
classical physics fate states. Mechanisms are routes of evolution between
classical physics fate states. Quantum mechanics are mechanisms, probable,
possible and actual mechanisms of getting from one to other classical physics
states WITHIN the expanse from cosmic singularity to the maximum expanded
universe and back to singularity states.

 

The universe is the archetype of
quantum within classical physics. This is the fractal oneness of the universe.
Astronomically there are two physics. A classical Newtonian physics behaviour
of and between galactic clusters, and a quantum physics behaviour WITHIN the
galactic clusters.

 

Life's Evolution Is The Quantum
Mechanics Of Biology.

UNRAVEL COMPLEXITIES OF GENETICS.
Extend Evolution/Natural Selection Backward To Genes/Genomes.

BOTH ARE ORGANISMS.

 

The origin-reason and the purpose-fate
of life are mechanistic, ethically and practically valueless. Life is the
cheapest commodity on Earth. Human life is just one of many nature's routes for
the natural survival of RNAs, the base Earth organism.

 

It is up to humans themselves to elect
the purpose and format of their life as individuals and as group-members.

 

 

Dov Henis

(Comments From 22nd Century)

Inception And Prevalence Of Western
Monotheism

http://pulse.yahoo.com/_2SF3CJ...

http://darwiniana.com/2011/04/...

=============================

 

C.

 

Adaptation And Genetics

Identify USA Science Problems

Enough Is Enough!

 

 

Concluding phrase of "A New
Evolutionary History of Primates"

http://www.sciencedaily.com/re...

 

"genetic underpinnings of human
adaptation"

 

This phrase displays basic ignorance of
the relationship between genetics and physiology/system adaptation.

It should be replaced with
"adaptation underpinnings of human genetics".

 

UNRAVEL COMPLEXITIES OF GENETICS.

Extend Evolution/Natural Selection
Backward To Genes/Genomes, BOTH ARE ORGANISMS.

 

IT IS ADAPTATION (CULTURE) THAT INDUCES
GENES' EXPRESSION MODIFICATION, NOT GENETICS THAT INDUCES ADAPTATION. Modified
genetic expression proceeds to energetically favor/enable adaptation.

 

 

Dov Henis

(comments from 22nd century)

http://universe-life.com/

http://universe-life.com/2011/...

http://dovhenis.wordpress.com/...

http://universe-life.com/2006/...

 

PS: How have the USA government and
nation/public come to allow a plainly obvious ("scientists", whatever
it means) trade-union, AAAS, to be involved in a host of national policies and
budgets matters? The motives/interests of the AAAS, just another trade-union,
are NOT always/necessarily congruent with the nation's/public welfare and it
definitely hinders very effectively advancement of basic science...DH

 

 

Avatar of:

Posts: 0

September 29, 2011

Imagine, just imagine, the interest and activity big bang in
science if/when finally freed from AAAS stock !!!

 

Science is not another, AAAS
trade-union peer-reviewed, religion.

It takes continuously  critical
refreshed thinking....

 

 

Whence And Whither

Extend Darwin-Einstein Horizon, EmD

 

 

EmD versus Emc

http://dovhenis.wordpress.com/...

 

E = mc2 relates E and m via constant c.

However, since E and c are constant m
must also be constant…?!

Yet for engineering-technology
applications the equation is practical,  fine.

 

E=Total[m(1 + D)] relates E and m via
the variable D. D is the sum total of distance, in ALL spatial
directions,  travelled by m since start of reconversion of m to E.

This relationship is science, not
engineering or technology. E is constant, m and D are variables. D cannot be
less than zero, and m varies with D. This is universal reality.

 

In this reality there is no missing
E.  E is there, transformed to mD.  mD is E.

In this reality there is no missing m.
 m is there, transformed to mD. mD is E.

 

Think about it. This is the
basis-essence of Evolution, of ALL evolutions. Evolutions are the quantum
mechanics of all processes.

 

 

Dov Henis

(comments from 22nd century)

 

-------------------------------------

 

“how species come to be…â€쳌

 

http://www.sciencenews.org/ind...

http://dovhenis.wordpress.com/...

 

What drives “species come to beâ€쳌 is what drives all
life/organisms to come to be,  i.e.  a proven successful route,
circumstantially evolved culture, that enhanced the RNAs’ constrained energy by
the culturally enhanced  RNAs’ proliferation, followed with accordingly
alternatively spliced expression.

 

This is evolution, i.e. enhanced constrained energy to
delay-postpone the universal conversion of mass-formats to energy, to the
energy that keeps fueling the expansion of the universe. This expansion will be
overcome by gravity upon depletion of the universe’s massfuel, and will be
followed by empansion for accelerating reverting of energy to mass all the way
back to singularity. The universe is an allmass allenergy poles affair.

 

Dov Henis

(comments from 22nd century)

http://dovhenis.wordpress.com/...

 

PS:

- It's culture that modifies genetics, that changes gene's
expression.  NOT vice versa.

- Epigenetics YOK. Alternative splicing is epiDNAtic, not
epigenetic.

- ALL life is RNAs evolution products. RNAs are Earth's
prime organism.

 

DH

 

========================

 

Update Comprehension Of Universe/Life
Evolution, Of RNA/DNA Mismatch-Relationship

http://dovhenis.wordpress.com/...

 

Genome is evolved by-for RNAs, like all
other Earth organisms:

 

THE National Science And Technology
Policy ISSUE In The USA (And Therefore Elsewhere...):

 

 

The early 20th century brief burst of
scientific evolution started expiring 90 years ago, at the birth of the
"scientists" (what does this mean?) trade-union AAAS.  True to
the AAAS trade-union interests the scientific evolution has grown into the
technology-industrial evolution, with evolved counter-enlightenment, greed
culture.

 

Re Science Education, it's about WHAT,
not about HOW, is taught.

"Scientists"
tradeunion-politically-controled "science" cannot be advanced/updated
regardless of education system...

See the C signature link...

 

Unravel Some Of Nature's Complexities,
A + B + C

(adnauseam, ad shown where these
data-based statements are wrong)

 

 

A.

 

UNRAVEL COMPLEXITIES OF GENETICS.

Extend Evolution/Natural Selection
Backward To Genes/Genomes, BOTH ARE ORGANISMS.

 

Again, Correct Some Figments Of Science
Imagination:

 

1. Dark energy and matter YOK.
Per  E=Total[m(1 + D)]  all the energy and matter of the universe are
accounted for.

Adopt space-massdistance concept,
mass-to-energy reconversion. 

 

2. Higgs Particle YOK. Mass forms below
some value of the above D.

 

3. Galactic clusters formed by
conglomeration?

Galactic clusters formed by Big-Bang's
dispersion, evidenced by their Newtonian behaviour including expansion
acceleration.

 

4. The universe expansion is fueled by
the mass-to-enrgy reconversion. Eventually, as expansion will slow down, will
run out of massfuel, gravity will overcome expansion and initiate empansion
back to singularity. The universe is a cyclic array of energy-mass dualism,
between all-energy and all-mass poles, under omnipresent gravity.

 

5. Natural Selection is a trait of
organisms, life?

No. Natural selection is ubiquitous for
ALL mass formats, all spin arrays. It derives from the expansion of the
universe. All mass formats, regardless of size and type, from black holes to
smallest particles, strive to increase their constrained energy in attempt to
postpone their own reconversion to energy, to the energy that fuels cosmic
expansion.

 

6. Life is an enigma?

Life is just another type of mass
array, a self-replicating mass array. Earth life is a replicating RNAs mass. It
has always been and still is an RNA world. ALL Earth's organisms are evolved
RNAs, evolved for maintaining-enhancing Earth's biosphere, for prolonging RNAs
survival.

 

7. Cells are Earth-life's primal
organisms?

NO. Earth's life day one was the day on
which RNA began replicating. RNAs, genes, are ORGANISMS. And so are their
evolved templates, (RNA and DNA) genomes, ORGANISMS, as evidenced by life's
chirality and by life's sleep.

 

8. Circadian Schmircadian sleep origin?

Sleep is inherent for life via the
RNAs, the primal Earth ORGANISMS originated and originally active only under
direct sunlight, in their pre-metabolism genesis era.

 

9. Epigenetics are heritable gene
functions changes not involving changes in DNA sequence?

The "heritable or enduring
changes" are epiDNAtics, not epigenetics. Alternative splicing is not
epigenetics, even if/when not involving alteration of the DNA sequence. Earth
life is an RNA world.

 

10.Genetics drive biology and culture
modifications?

NO. It is culture that modifies
genetics, not genetics that modifies culture. Culture modifies genetics simply
via the evolutionary natural selection process of the RNA ORGANISMS. Likewise
many natural genetic changes are due to aging and/or circumstantial effects on
the genes and/or genomes ORGANISMS, similar to aging and/or evolutionary
processes in monocell communities or in multicelled organisms.

 

 

SCIENCE SHOULD UNFREEZE. SCIENCE SHOULD
ADJUST ITS VISION, COMPREHENSION AND CONCEPTS.

 

 

Dov Henis

(Comments From 22nd Century)

 

Seed of Human-Chimp Genomes Diversity

http://dovhenis.wordpress.com/...

03.2010 Updated Life Manifest

http://dovhenis.wordpress.com/...

Evolution, Natural Selection, Derive
From Cosmic Expansion

http://darwiniana.com/2010/09/...

Rethink Evolution/Natural Selection

http://darwiniana.com/2011/03/...

 

==========================

 

B.

 

Quantum Mechanics Of Life

Life's Evolution Is The Quantum
Mechanics Of Biology

http://pulse.yahoo.com/_2SF3CJ...

 

From "Essence Of Quantum
Mechanics"

http://pulse.yahoo.com/_2SF3CJ...

 

The universe, and life within it, are
not just conglomerations of mechanisms. The universe, and life within it, have
come into being by the nature of energy-mass dualism, and their fate, their
final outcome, is governed by this dualism. The genesis and, most probable
cyclic, existence of the universe are governed by the energy-mass relationship.

 

Energy-mass relationship governs also
the routes, the mechanisms, of cosmic and life evolutions.

 

Mechanisms do not set/determine the
classical physics fate states. Mechanisms are routes of evolution between
classical physics fate states. Quantum mechanics are mechanisms, probable,
possible and actual mechanisms of getting from one to other classical physics
states WITHIN the expanse from cosmic singularity to the maximum expanded
universe and back to singularity states.

 

The universe is the archetype of
quantum within classical physics. This is the fractal oneness of the universe.
Astronomically there are two physics. A classical Newtonian physics behaviour
of and between galactic clusters, and a quantum physics behaviour WITHIN the
galactic clusters.

 

Life's Evolution Is The Quantum
Mechanics Of Biology.

UNRAVEL COMPLEXITIES OF GENETICS.
Extend Evolution/Natural Selection Backward To Genes/Genomes.

BOTH ARE ORGANISMS.

 

The origin-reason and the purpose-fate
of life are mechanistic, ethically and practically valueless. Life is the
cheapest commodity on Earth. Human life is just one of many nature's routes for
the natural survival of RNAs, the base Earth organism.

 

It is up to humans themselves to elect
the purpose and format of their life as individuals and as group-members.

 

 

Dov Henis

(Comments From 22nd Century)

Inception And Prevalence Of Western
Monotheism

http://pulse.yahoo.com/_2SF3CJ...

http://darwiniana.com/2011/04/...

=============================

 

C.

 

Adaptation And Genetics

Identify USA Science Problems

Enough Is Enough!

 

 

Concluding phrase of "A New
Evolutionary History of Primates"

http://www.sciencedaily.com/re...

 

"genetic underpinnings of human
adaptation"

 

This phrase displays basic ignorance of
the relationship between genetics and physiology/system adaptation.

It should be replaced with
"adaptation underpinnings of human genetics".

 

UNRAVEL COMPLEXITIES OF GENETICS.

Extend Evolution/Natural Selection
Backward To Genes/Genomes, BOTH ARE ORGANISMS.

 

IT IS ADAPTATION (CULTURE) THAT INDUCES
GENES' EXPRESSION MODIFICATION, NOT GENETICS THAT INDUCES ADAPTATION. Modified
genetic expression proceeds to energetically favor/enable adaptation.

 

 

Dov Henis

(comments from 22nd century)

http://universe-life.com/

http://universe-life.com/2011/...

http://dovhenis.wordpress.com/...

http://universe-life.com/2006/...

 

PS: How have the USA government and
nation/public come to allow a plainly obvious ("scientists", whatever
it means) trade-union, AAAS, to be involved in a host of national policies and
budgets matters? The motives/interests of the AAAS, just another trade-union,
are NOT always/necessarily congruent with the nation's/public welfare and it
definitely hinders very effectively advancement of basic science...DH

 

 

Avatar of:

Posts: 0

September 29, 2011

Imagine, just imagine, the interest and activity big bang in
science if/when finally freed from AAAS stock !!!

 

Science is not another, AAAS
trade-union peer-reviewed, religion.

It takes continuously  critical
refreshed thinking....

 

 

Whence And Whither

Extend Darwin-Einstein Horizon, EmD

 

 

EmD versus Emc

http://dovhenis.wordpress.com/...

 

E = mc2 relates E and m via constant c.

However, since E and c are constant m
must also be constant…?!

Yet for engineering-technology
applications the equation is practical,  fine.

 

E=Total[m(1 + D)] relates E and m via
the variable D. D is the sum total of distance, in ALL spatial
directions,  travelled by m since start of reconversion of m to E.

This relationship is science, not
engineering or technology. E is constant, m and D are variables. D cannot be
less than zero, and m varies with D. This is universal reality.

 

In this reality there is no missing
E.  E is there, transformed to mD.  mD is E.

In this reality there is no missing m.
 m is there, transformed to mD. mD is E.

 

Think about it. This is the
basis-essence of Evolution, of ALL evolutions. Evolutions are the quantum
mechanics of all processes.

 

 

Dov Henis

(comments from 22nd century)

 

-------------------------------------

 

“how species come to be…â€쳌

 

http://www.sciencenews.org/ind...

http://dovhenis.wordpress.com/...

 

What drives “species come to beâ€쳌 is what drives all
life/organisms to come to be,  i.e.  a proven successful route,
circumstantially evolved culture, that enhanced the RNAs’ constrained energy by
the culturally enhanced  RNAs’ proliferation, followed with accordingly
alternatively spliced expression.

 

This is evolution, i.e. enhanced constrained energy to
delay-postpone the universal conversion of mass-formats to energy, to the
energy that keeps fueling the expansion of the universe. This expansion will be
overcome by gravity upon depletion of the universe’s massfuel, and will be
followed by empansion for accelerating reverting of energy to mass all the way
back to singularity. The universe is an allmass allenergy poles affair.

 

Dov Henis

(comments from 22nd century)

http://dovhenis.wordpress.com/...

 

PS:

- It's culture that modifies genetics, that changes gene's
expression.  NOT vice versa.

- Epigenetics YOK. Alternative splicing is epiDNAtic, not
epigenetic.

- ALL life is RNAs evolution products. RNAs are Earth's
prime organism.

 

DH

 

========================

 

Update Comprehension Of Universe/Life
Evolution, Of RNA/DNA Mismatch-Relationship

http://dovhenis.wordpress.com/...

 

Genome is evolved by-for RNAs, like all
other Earth organisms:

 

THE National Science And Technology
Policy ISSUE In The USA (And Therefore Elsewhere...):

 

 

The early 20th century brief burst of
scientific evolution started expiring 90 years ago, at the birth of the
"scientists" (what does this mean?) trade-union AAAS.  True to
the AAAS trade-union interests the scientific evolution has grown into the
technology-industrial evolution, with evolved counter-enlightenment, greed
culture.

 

Re Science Education, it's about WHAT,
not about HOW, is taught.

"Scientists"
tradeunion-politically-controled "science" cannot be advanced/updated
regardless of education system...

See the C signature link...

 

Unravel Some Of Nature's Complexities,
A + B + C

(adnauseam, ad shown where these
data-based statements are wrong)

 

 

A.

 

UNRAVEL COMPLEXITIES OF GENETICS.

Extend Evolution/Natural Selection
Backward To Genes/Genomes, BOTH ARE ORGANISMS.

 

Again, Correct Some Figments Of Science
Imagination:

 

1. Dark energy and matter YOK.
Per  E=Total[m(1 + D)]  all the energy and matter of the universe are
accounted for.

Adopt space-massdistance concept,
mass-to-energy reconversion. 

 

2. Higgs Particle YOK. Mass forms below
some value of the above D.

 

3. Galactic clusters formed by
conglomeration?

Galactic clusters formed by Big-Bang's
dispersion, evidenced by their Newtonian behaviour including expansion
acceleration.

 

4. The universe expansion is fueled by
the mass-to-enrgy reconversion. Eventually, as expansion will slow down, will
run out of massfuel, gravity will overcome expansion and initiate empansion
back to singularity. The universe is a cyclic array of energy-mass dualism,
between all-energy and all-mass poles, under omnipresent gravity.

 

5. Natural Selection is a trait of
organisms, life?

No. Natural selection is ubiquitous for
ALL mass formats, all spin arrays. It derives from the expansion of the
universe. All mass formats, regardless of size and type, from black holes to
smallest particles, strive to increase their constrained energy in attempt to
postpone their own reconversion to energy, to the energy that fuels cosmic
expansion.

 

6. Life is an enigma?

Life is just another type of mass
array, a self-replicating mass array. Earth life is a replicating RNAs mass. It
has always been and still is an RNA world. ALL Earth's organisms are evolved
RNAs, evolved for maintaining-enhancing Earth's biosphere, for prolonging RNAs
survival.

 

7. Cells are Earth-life's primal
organisms?

NO. Earth's life day one was the day on
which RNA began replicating. RNAs, genes, are ORGANISMS. And so are their
evolved templates, (RNA and DNA) genomes, ORGANISMS, as evidenced by life's
chirality and by life's sleep.

 

8. Circadian Schmircadian sleep origin?

Sleep is inherent for life via the
RNAs, the primal Earth ORGANISMS originated and originally active only under
direct sunlight, in their pre-metabolism genesis era.

 

9. Epigenetics are heritable gene
functions changes not involving changes in DNA sequence?

The "heritable or enduring
changes" are epiDNAtics, not epigenetics. Alternative splicing is not
epigenetics, even if/when not involving alteration of the DNA sequence. Earth
life is an RNA world.

 

10.Genetics drive biology and culture
modifications?

NO. It is culture that modifies
genetics, not genetics that modifies culture. Culture modifies genetics simply
via the evolutionary natural selection process of the RNA ORGANISMS. Likewise
many natural genetic changes are due to aging and/or circumstantial effects on
the genes and/or genomes ORGANISMS, similar to aging and/or evolutionary
processes in monocell communities or in multicelled organisms.

 

 

SCIENCE SHOULD UNFREEZE. SCIENCE SHOULD
ADJUST ITS VISION, COMPREHENSION AND CONCEPTS.

 

 

Dov Henis

(Comments From 22nd Century)

 

Seed of Human-Chimp Genomes Diversity

http://dovhenis.wordpress.com/...

03.2010 Updated Life Manifest

http://dovhenis.wordpress.com/...

Evolution, Natural Selection, Derive
From Cosmic Expansion

http://darwiniana.com/2010/09/...

Rethink Evolution/Natural Selection

http://darwiniana.com/2011/03/...

 

==========================

 

B.

 

Quantum Mechanics Of Life

Life's Evolution Is The Quantum
Mechanics Of Biology

http://pulse.yahoo.com/_2SF3CJ...

 

From "Essence Of Quantum
Mechanics"

http://pulse.yahoo.com/_2SF3CJ...

 

The universe, and life within it, are
not just conglomerations of mechanisms. The universe, and life within it, have
come into being by the nature of energy-mass dualism, and their fate, their
final outcome, is governed by this dualism. The genesis and, most probable
cyclic, existence of the universe are governed by the energy-mass relationship.

 

Energy-mass relationship governs also
the routes, the mechanisms, of cosmic and life evolutions.

 

Mechanisms do not set/determine the
classical physics fate states. Mechanisms are routes of evolution between
classical physics fate states. Quantum mechanics are mechanisms, probable,
possible and actual mechanisms of getting from one to other classical physics
states WITHIN the expanse from cosmic singularity to the maximum expanded
universe and back to singularity states.

 

The universe is the archetype of
quantum within classical physics. This is the fractal oneness of the universe.
Astronomically there are two physics. A classical Newtonian physics behaviour
of and between galactic clusters, and a quantum physics behaviour WITHIN the
galactic clusters.

 

Life's Evolution Is The Quantum
Mechanics Of Biology.

UNRAVEL COMPLEXITIES OF GENETICS.
Extend Evolution/Natural Selection Backward To Genes/Genomes.

BOTH ARE ORGANISMS.

 

The origin-reason and the purpose-fate
of life are mechanistic, ethically and practically valueless. Life is the
cheapest commodity on Earth. Human life is just one of many nature's routes for
the natural survival of RNAs, the base Earth organism.

 

It is up to humans themselves to elect
the purpose and format of their life as individuals and as group-members.

 

 

Dov Henis

(Comments From 22nd Century)

Inception And Prevalence Of Western
Monotheism

http://pulse.yahoo.com/_2SF3CJ...

http://darwiniana.com/2011/04/...

=============================

 

C.

 

Adaptation And Genetics

Identify USA Science Problems

Enough Is Enough!

 

 

Concluding phrase of "A New
Evolutionary History of Primates"

http://www.sciencedaily.com/re...

 

"genetic underpinnings of human
adaptation"

 

This phrase displays basic ignorance of
the relationship between genetics and physiology/system adaptation.

It should be replaced with
"adaptation underpinnings of human genetics".

 

UNRAVEL COMPLEXITIES OF GENETICS.

Extend Evolution/Natural Selection
Backward To Genes/Genomes, BOTH ARE ORGANISMS.

 

IT IS ADAPTATION (CULTURE) THAT INDUCES
GENES' EXPRESSION MODIFICATION, NOT GENETICS THAT INDUCES ADAPTATION. Modified
genetic expression proceeds to energetically favor/enable adaptation.

 

 

Dov Henis

(comments from 22nd century)

http://universe-life.com/

http://universe-life.com/2011/...

http://dovhenis.wordpress.com/...

http://universe-life.com/2006/...

 

PS: How have the USA government and
nation/public come to allow a plainly obvious ("scientists", whatever
it means) trade-union, AAAS, to be involved in a host of national policies and
budgets matters? The motives/interests of the AAAS, just another trade-union,
are NOT always/necessarily congruent with the nation's/public welfare and it
definitely hinders very effectively advancement of basic science...DH

 

 

Avatar of:

Posts: 0

October 4, 2011

Establishment of a reference epigenome must begin somewhere.  Perhaps someday, after many many samplings, it may be discovered that some sequences are more typical, or some variations have limits and a midline between them.  Perhaps for each "gene" there will be variations that correlate more typically to it.

For now any baseline to measure variances from is better than no baseline at all.

It's interesting to see how long it is taking to reach a globalized metric standard to be taught in primary and secondary schools, but hopefully a central standard model for measuring epigenetic variances (if indicated at all) would be standardized sooner and would not take centuries for mankind to collectively get on the same page with it.

Avatar of:

Posts: 0

October 4, 2011

Establishment of a reference epigenome must begin somewhere.  Perhaps someday, after many many samplings, it may be discovered that some sequences are more typical, or some variations have limits and a midline between them.  Perhaps for each "gene" there will be variations that correlate more typically to it.

For now any baseline to measure variances from is better than no baseline at all.

It's interesting to see how long it is taking to reach a globalized metric standard to be taught in primary and secondary schools, but hopefully a central standard model for measuring epigenetic variances (if indicated at all) would be standardized sooner and would not take centuries for mankind to collectively get on the same page with it.

Avatar of: Guest

Anonymous

October 4, 2011

Establishment of a reference epigenome must begin somewhere.  Perhaps someday, after many many samplings, it may be discovered that some sequences are more typical, or some variations have limits and a midline between them.  Perhaps for each "gene" there will be variations that correlate more typically to it.

For now any baseline to measure variances from is better than no baseline at all.

It's interesting to see how long it is taking to reach a globalized metric standard to be taught in primary and secondary schools, but hopefully a central standard model for measuring epigenetic variances (if indicated at all) would be standardized sooner and would not take centuries for mankind to collectively get on the same page with it.

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