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Chronic Fatigue Researcher Fired

Researcher who found connection between virus and chronic fatigue fired for not releasing her research samples.

By | October 4, 2011

WIKIMEDIA COMMONS, PAUL SAPIANO

Judy Mikovits, the lead researcher of a study that suggested that the retrovirus XMRV might cause chronic fatigue syndrome was fired from her institution for refusing to share her cell lines with another researcher at the Whittemore Peterson Institute for Neuro-Immune Disease, where she worked, reported the Wall Street Journal Health Blog.

Her study was partially retracted last month (September 22), when two of the authors of paper detected contamination in their samples. Still, Mikovits stood by the original findings.  When the president of the Whittemore Peterson Institute requested the cell lines for another scientist at the institute, Mikovitz refused.  About a week later, she was fired.

The majority of the researchers in the field agree that there is no connection between XMRV and chronic fatigue, and say that the millions spent on further research have sufficiently discredited the claim.  Sufferers of chronic fatigue, however, have continued to uphold the link, as there is currently little else to explain the symptoms.

(Hat tip to FierceBiotech.)

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Avatar of: scooter

Anonymous

October 4, 2011

We don't know what researcher wanted to use the cells.  It could be that the chain of custody was important to the research.  Mikovits is the most senior researcher there.  There may be a conflict of interest between the research lab and the commercial lab VIPdx.  These people have been under great strain with all the demands to participate in testing others' assays.

Avatar of:

Posts: 0

October 4, 2011

We don't know what researcher wanted to use the cells.  It could be that the chain of custody was important to the research.  Mikovits is the most senior researcher there.  There may be a conflict of interest between the research lab and the commercial lab VIPdx.  These people have been under great strain with all the demands to participate in testing others' assays.

Avatar of:

Posts: 0

October 4, 2011

We don't know what researcher wanted to use the cells.  It could be that the chain of custody was important to the research.  Mikovits is the most senior researcher there.  There may be a conflict of interest between the research lab and the commercial lab VIPdx.  These people have been under great strain with all the demands to participate in testing others' assays.

Avatar of:

Posts: 0

October 5, 2011

"Sufferers of chronic fatigue, however, have continued to uphold the link, as there is currently little else to explain the symptoms."

There is plenty of evidence to explain the symptoms. Chronic lowgrade hemolysis. It is evidenced in the symptoms and the theories and treatment. Fatigue is highly expressed in an oxidative stress induced state as evidenced in paroxysmal nocturnal hemoglobinuria (PNH) .
"Data suggest that fatigue experienced by patients with PNH is related directly to hemolysis - the red blood cell destruction that defines the disease - and can be improved independent of correction of anemia"
They believe fish poison is a "human model of CFS" and the plant sugar D-mannitol has been tested.
"Reversed by D-mannitol"
"Chronic phase lipids in sera of chronic fatigue syndrome (CFS),chronic ciguatera fish poisoning (CCFP), hepatitis B, and cancer with antigenic epitope resembling ciguatoxin, as assessed with MAb-CTX.""Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: A comparison with other osmotic agents and free radical scavengers"
What connection between the fact fatigue is caused by hemolysis in PNH and chronic fatigue is thought to be caused by the tick which ALSO causes hemolysis ? We know fish toxin causes hemolysis. IS hemolysis somehow involved in the fatigue ? WHAT could be causing the hemolysis AND fatigue in all ? "Ciguatera Epitope is Found to Kill Red Blood Cells; Implications for Red Cell Lysis, Sequestration, Rheology and Blood Volume""This study provides the first evidence of hemolytic activity associated with B. burgdorferi"
Another disease which has a high rate of hemolysis is porphyria.
THAT disease has been treated with homeopathic snake venom . Like cures like. Hemolysis cures hemolysis. 
In paroxysmal nocturnal hemoglobinuria (PNH) tocopherol phosphate has been used and shown to help . Lack of tocopherol causes red blood cell lysis / hemolysis.
IS hemolysis and a lack of tocopherol / vitamin E involved in chronic fatigue ? 

Avatar of:

Posts: 0

October 5, 2011

"Sufferers of chronic fatigue, however, have continued to uphold the link, as there is currently little else to explain the symptoms."

There is plenty of evidence to explain the symptoms. Chronic lowgrade hemolysis. It is evidenced in the symptoms and the theories and treatment. Fatigue is highly expressed in an oxidative stress induced state as evidenced in paroxysmal nocturnal hemoglobinuria (PNH) .
"Data suggest that fatigue experienced by patients with PNH is related directly to hemolysis - the red blood cell destruction that defines the disease - and can be improved independent of correction of anemia"
They believe fish poison is a "human model of CFS" and the plant sugar D-mannitol has been tested.
"Reversed by D-mannitol"
"Chronic phase lipids in sera of chronic fatigue syndrome (CFS),chronic ciguatera fish poisoning (CCFP), hepatitis B, and cancer with antigenic epitope resembling ciguatoxin, as assessed with MAb-CTX.""Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: A comparison with other osmotic agents and free radical scavengers"
What connection between the fact fatigue is caused by hemolysis in PNH and chronic fatigue is thought to be caused by the tick which ALSO causes hemolysis ? We know fish toxin causes hemolysis. IS hemolysis somehow involved in the fatigue ? WHAT could be causing the hemolysis AND fatigue in all ? "Ciguatera Epitope is Found to Kill Red Blood Cells; Implications for Red Cell Lysis, Sequestration, Rheology and Blood Volume""This study provides the first evidence of hemolytic activity associated with B. burgdorferi"
Another disease which has a high rate of hemolysis is porphyria.
THAT disease has been treated with homeopathic snake venom . Like cures like. Hemolysis cures hemolysis. 
In paroxysmal nocturnal hemoglobinuria (PNH) tocopherol phosphate has been used and shown to help . Lack of tocopherol causes red blood cell lysis / hemolysis.
IS hemolysis and a lack of tocopherol / vitamin E involved in chronic fatigue ? 

Avatar of: Tom Hennessy

Tom Hennessy

Posts: 1457

October 5, 2011

"Sufferers of chronic fatigue, however, have continued to uphold the link, as there is currently little else to explain the symptoms."

There is plenty of evidence to explain the symptoms. Chronic lowgrade hemolysis. It is evidenced in the symptoms and the theories and treatment. Fatigue is highly expressed in an oxidative stress induced state as evidenced in paroxysmal nocturnal hemoglobinuria (PNH) .
"Data suggest that fatigue experienced by patients with PNH is related directly to hemolysis - the red blood cell destruction that defines the disease - and can be improved independent of correction of anemia"
They believe fish poison is a "human model of CFS" and the plant sugar D-mannitol has been tested.
"Reversed by D-mannitol"
"Chronic phase lipids in sera of chronic fatigue syndrome (CFS),chronic ciguatera fish poisoning (CCFP), hepatitis B, and cancer with antigenic epitope resembling ciguatoxin, as assessed with MAb-CTX.""Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: A comparison with other osmotic agents and free radical scavengers"
What connection between the fact fatigue is caused by hemolysis in PNH and chronic fatigue is thought to be caused by the tick which ALSO causes hemolysis ? We know fish toxin causes hemolysis. IS hemolysis somehow involved in the fatigue ? WHAT could be causing the hemolysis AND fatigue in all ? "Ciguatera Epitope is Found to Kill Red Blood Cells; Implications for Red Cell Lysis, Sequestration, Rheology and Blood Volume""This study provides the first evidence of hemolytic activity associated with B. burgdorferi"
Another disease which has a high rate of hemolysis is porphyria.
THAT disease has been treated with homeopathic snake venom . Like cures like. Hemolysis cures hemolysis. 
In paroxysmal nocturnal hemoglobinuria (PNH) tocopherol phosphate has been used and shown to help . Lack of tocopherol causes red blood cell lysis / hemolysis.
IS hemolysis and a lack of tocopherol / vitamin E involved in chronic fatigue ? 

Avatar of: catleyar

Anonymous

October 6, 2011

so she really has it in hand or not?  It just doesnt make sense to me that she chose to lose the job and to be discredited by others for such cell lines.  If she has it contaminated just like the other two, explanation about that should be acceptable.

Avatar of:

Posts: 0

October 6, 2011

so she really has it in hand or not?  It just doesnt make sense to me that she chose to lose the job and to be discredited by others for such cell lines.  If she has it contaminated just like the other two, explanation about that should be acceptable.

Avatar of:

Posts: 0

October 6, 2011

so she really has it in hand or not?  It just doesnt make sense to me that she chose to lose the job and to be discredited by others for such cell lines.  If she has it contaminated just like the other two, explanation about that should be acceptable.

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