Arsenic Bug's Genome Sequenced

Researchers have mapped out the DNA of what some scientists claim to be an arsenic loving bacterium.

By | December 7, 2011

THe newly-sequenced GFAJ-1Wikimedia Commons, NASA

The newly-sequenced GFAJ-1

The GFAJ-1 bacterium, which whipped up controversy a year ago when researchers claimed that it could survive and grow using arsenic instead of phosphorus, has been sequenced. Scientists from the University of Illinois, Chicago, (UIC) and elsewhere posted GFAJ-1's genome sequence—which contains 3,400 genes within its 3.5 million basepairs—in Genbank last week.

UIC arsenic microbiologist Simon Silver, a vocal critic of the claim that the bacteria can thrive on arsenic, told ScienceInsider that the sequence doesn't settle the debate over whether the organism can incorporate arsenic into its DNA, but it does reveal that GFAJ-1 has fewer genes known to help organisms survive in high-arsenic environments than E. coli does. Silver added that he's not hopeful that the GFAJ-1 sequence will convince the researchers who published the initial claim that they're wrong. "This sort of stuff never gets resolved," he said. "It eventually goes away."

Felisa Wolfe-Simon, the NASA Astrobiology Research Fellow (now at Lawrence Berkeley National Laboratory) who led the team that published those initial results in Science, told ScienceInsider that she welcomed the publication of the bacterium's genome, calling it "an important step forward." Wolfe-Simon, Silver, and their collaborators continue to work with the GFAJ-1 bacterium to better understand its apparent ability to withstand arsenic poisoning. One researcher is even openly blogging about her attempt to replicate Wolfe-Simon’s experiments.

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. What Budget Cuts Might Mean for US Science
    News Analysis What Budget Cuts Might Mean for US Science

    A look at the historical effects of downsized research funding suggests that the Trump administration’s proposed budget could hit early-career scientists the hardest.  

  2. UC Berkeley Receives CRISPR Patent in Europe
    Daily News UC Berkeley Receives CRISPR Patent in Europe

    The European Patent Office will grant patent rights over the use of CRISPR in all cell types to a University of California team, contrasting with a recent decision in the U.S.

  3. Opinion: On “The Impact Factor Fallacy”
  4. Unstructured Proteins Help Tardigrades Survive Desiccation
Business Birmingham