World’s First Chimeric Monkeys

Researchers have bred monkeys derived from six different monkey parents.

By | January 5, 2012

Two rhesus monkeys made from a combination of embryonic cells from six different monkey embryos OREGON HEALTH AND SCIENCE UNIVERSITY

Researchers at the Oregon National Primate Research Center have generated the world’s first ever chimeric primates—three young monkeys derived from six distinct genomes, according to a paper published today (January 5) in Cell.

The infants—a set of twins and a singleton—were generated from 4-day-old embryos of six different rhesus monkeys stuck together early in development, then implanted into five adult females. Tests on the fetuses showed that all of the infants’ organs and tissues contained a mixture of cells carrying the different genomes, and all three monkeys that made it term appear to be healthy with no birth defects.

Although the embryos grow together into one larger embryo, "the cells never fuse," Shoukhrat Mitalipov, an associate scientist at the Oregon National Primate Research Center who led the research, told The Guardian. Instead, "they stay together and work together to form tissues and organs. The possibilities for science are enormous," he said, such as aiding the study of embryonic development and cellular differentiation.

Chimeric mice were first bred in the 1960s, with chimeric rats, rabbits, sheep, and cattle appearing over the last half a century. "I don't think it's ever been done before in a primate species," Mitalipov told OregonLive.

Roku and Hex from OHSU News on Vimeo.

 

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Comments

Avatar of:

Posts: 0

January 7, 2012

Chimeras aren't "bred". They are manufactured and implanted.

Avatar of:

Posts: 0

January 7, 2012

Chimeras aren't "bred". They are manufactured and implanted.

Avatar of: Ellen Hunt

Ellen Hunt

Posts: 74

January 7, 2012

Chimeras aren't "bred". They are manufactured and implanted.

Avatar of: TheSciAdmin

TheSciAdmin

Posts: 56

January 9, 2012

Hi Ellen. Good point. The story has been updated and a correction amended.

Thanks for reading!
~Jef Akst, editor, The Scientist

Avatar of:

Posts: 0

January 9, 2012

Hi Ellen. Good point. The story has been updated and a correction amended.

Thanks for reading!
~Jef Akst, editor, The Scientist

Avatar of:

Posts: 0

January 9, 2012

Hi Ellen. Good point. The story has been updated and a correction amended.

Thanks for reading!
~Jef Akst, editor, The Scientist

Popular Now

  1. Unstructured Proteins Help Tardigrades Survive Desiccation
  2. What Budget Cuts Might Mean for US Science
    News Analysis What Budget Cuts Might Mean for US Science

    A look at the historical effects of downsized research funding suggests that the Trump administration’s proposed budget could hit early-career scientists the hardest.  

  3. Inflammation Drives Gut Bacteria Evolution
  4. Opinion: On “The Impact Factor Fallacy”
Business Birmingham