Designing Transition-State Inhibitors

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

By | May 1, 2012

Infographic: Designing Transition-State Inhibitors
View full size JPG | PDF
LUCY READING-IKKANDA

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. In order to replicate the structure of an enzyme’s transition state, which only lasts a few femtoseconds, we use computational and experimental methods to reveal the shape, atom by atom.

Read the full story.

Advertisement

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. Next Generation: Nanotube Scaffolds Reconnect Spinal Neurons
  2. Mapping the Human Connectome
    Daily News Mapping the Human Connectome

    A new map of human cortex combines data from multiple imaging modalities and comprises 180 distinct regions.

  3. Will Organs-in-a-Dish Ever Replace Animal Models?
  4. Your Office Has a Distinct Microbiome
RayBiotech