Cell-based model systems are powerful tools for studying signaling pathways, deciphering disease mechanisms, and predicting drug activities. To highlight some of the exciting areas where the use of cell models is pushing the boundaries in science, technology, and therapy, ATCC is partnering with The Scientist to present a series of webinars.
The 3-part series will bring together expert researchers to talk about current innovations, applications, and challenges in using cell-based model systems, while highlighting future trends. In each webinar, the panelists will give a brief presentation and then be available to address questions posed by the attendees in real time.
ATCC has been an integral part of biological research for more than 88 years, and is proud to partner with The Scientist in presenting this webinar series on innovative cell research.
Focus on Stem Cell Research
Stem cells provide a unique method for in vitro modeling and screening in a physiologically relevant environment that is both consistent and replicable. Induced pluripotent stem cells (iPSCs), in particular, present a noncontroversial approach for modeling human physiology and disease and for studying the mechanism of action of a drug and its efficacy and safety. However, technical challenges remain to be overcome in culturing and maintaining these cells and a number of researchers remain skeptical about the relevance and validity of results obtained using these cells. Our panel of experts will share their perspectives on the pros and cons of using iPSCs for research and attendees can interact with them during the live webinar by asking questions and sharing their concerns.
Stephen Chang, Ph.D., Vice President of Research and Development, New York Stem Cell Foundation
Hirdesh Uppal, Ph.D., Scientist, Safety Assessment & Development Sciences, Genentech Inc.
Joseph C. Wu, M.D., Ph.D., Director, Stanford Cardiovascular Institute, Professor, Department of Medicine/Cardiology & Radiology, Stanford University School of Medicine
Heightened resistance to antibiotic drugs and the reduced potency of available vaccines clearly indicate that understanding the dynamics of host-pathogen interactions and the resulting modulation in cell signaling is increasingly imperative. A clearer picture of the underlying molecular mechanisms will result in the development of novel vaccines and therapeutic interventions that will enhance host immunity, circumvent pathogen evasion strategies, and prevent the likelihood of serious infections. Our panel of experts will provide some insight into the progress being made in the exciting study of host-pathogen interactions, and will discuss some of the strategies and technologies they have used when working various viruses, bacteria, and other pathogens.
Abraham Brass, MD, PhD, Assistant Professor, Department of Microbiology and Physiological Systems, University of Massachusetts Medical School
Nihal Altan-Bonnet, PhD, Assistant Professor, Laboratory of Host-Pathogen Dynamics, Department of Biological Sciences, Rutgers University
Scott Grieshaber PhD, Assistant Professor, Department of Oral Biology, School of Dentistry, University of Florida
Focus on Cancer Research
In order to understand the complex mechanisms of tumorigenesis, detecting, interpreting, and exploiting different types of information from human cancer cells, is now a central focus for both basic researchers and drug development scientists. Our panel of experts will provide some insight into the progress being made, while highlighting the factors that have made it possible. They will discuss the imperative need to start out with the highest-quality cells and biological samples for research, to establish rigorous standards for sample and data collection and storage, and to develop a collaboration platform for the effective analysis and sharing of data obtained from disparate sources.
Jaspal Khillan, PhD, Research Associate Professor, Department of Microbiology & Molecular Genetics, University of Pittsburgh
Sophie Lelievre, DVM, LLM, PhD, Associate Professor, Department of Basic Medical Sciences and Associate Director, Discovery Groups, NCI-designated Purdue Center for Cancer Research, Purdue University
Lesley Mathews, PhD, Research Scientist, Biomolecular Screening and Profiling/Probe Development, National Institutes of Health (NIH)