Physiologist Faked Data

A Case Western Reserve University researcher is found guilty of altering the number of samples and results to inflate the statistical significance of his findings.

By | February 5, 2013

WIKIMEDIA, GALLO & SPERO LLPThe Office of Research Integrity (ORI) has censured Bryan William Doreian, a former physiology researcher at Case Western Reserve University in Cleveland, for falsifying data in his PhD dissertation, a 2009 paper in the Molecular Biology of the Cell, and a manuscript submitted to Nature Medicine.

Investigators found that Doreian, previously a postdoctoral fellow studying the behavior of adrenalin-containing cells called chromaffin cells during stress response, had massaged numerical values to improve the statistical significance of his results. Among seven separate transgressions listed by the ORI, Doreian was found to have falsified the quantification of particular proteins in response to different stimuli, as reported in the published paper, by claiming he’d replicated the experiment in 15 samples when he’d actually done it on fewer.

Doreian agreed to request the retraction of the published paper, cited 14 times according to ISI Web of Knowledge. He also agreed to have his research supervised for 3 years. That may be unnecessary, however, because Doreian seems to have found a career outside science as the head of a company that helps attorneys pass the bar, Retraction Watch reported.


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Avatar of: Paul Stein

Paul Stein

Posts: 164

February 6, 2013

A person who committed fraud is now helping attorneys pass the bar.  Okay folks, that's so ironically laughable, I'm not even going to go there.  


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