Advertisement

Leukemia Linked to Changes in Womb

Genetic changes that may initiate childhood leukemia could originate while the baby is still in utero.

By | April 10, 2013

Ultrasound of a pair of twins in uteroWIKIMEDIA, ENTROPY 1963Researchers at the Institute of Cancer Researcher in London honed in on a single mutation occurring in two identical twins. The mutation, the scientists reasoned, must have arisen in the womb, according to research published this week (April 8) in the Proceedings of the National Academy of Sciences.

“Studies like this could reveal new ways to target the very roots of cancer and help us better understand how the disease develops over time,” Julie Sharp of Cancer Research UK told BBC News.

The researchers sequenced the genomes of leukemic cells in a pair of twins with acute lymphoblastic leukemia (ALL), the most common form of leukemia in children. The team identified one mutation in a known leukemia-causing gene that was shared by the twins, as well as another 22 leukemia-related mutations that were not shared. The authors suggested that the mutation might have arisen in one twin and was passed to the other in the womb through a shared placenta. 

Advertisement

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo
Advertisement
RayBiotech
RayBiotech

Popular Now

  1. Most Earth-like Planet Found
  2. AAAAA Is for Arrested Translation
  3. Four-legged Snake Fossil Found
  4. The Sum of Our Parts
    Features The Sum of Our Parts

    Putting the microbiome front and center in health care, in preventive strategies, and in health-risk assessments could stem the epidemic of noncommunicable diseases.

Advertisement
Advertisement