Extreme Expression

Researchers sequence the transcriptome of the Antarctic-dwelling bald notothen fish.

By | August 26, 2013

WIKIMEDIA, LIAM QUINNThe bald notothen (Pagothenia borchgrevinki) is a fish that typically dwells in the icy waters of Antarctica, but given time to acclimatize to incremental temperature increases, it can also handle warmer waters. Because the fish is often used as a model for studies on cold adaptation, Kevin Bilyk and Chi-Hing Christina Cheng from the University of Illinois at Urbana-Champaign sought to unearth gene expression signatures within the P. borchgrevinki transcriptome that might hold clues as to how it survives such extreme cold.
In a study appearing in BMC Genomics today (August 26), Bilyk and Cheng report having sequenced multiple tissue transcriptomes from both native and heat-exposed notothen fish. They then compared the transcriptome sequences with those from the tropical water-dwelling zebrafish, identifying 58 P. borchgrevinki-specific signatures that could hold the key to survival in extreme cold environments.
The researchers “hope to unravel the molecular mechanisms that enable the fish to survive both extreme cold and warmer temperatures—a feature that may serve the fish well as climate change threatens the temperature of polar waters,” the journal’s publisher, BioMed Central, noted in a press release.
In their paper, the authors note that they are now working to investigate the transcriptional changes that occur in the fish during its first four days of exposure to 4°C “in order to better understand how their response to heat has been influenced by the long evolution of Antarctic notothenioid fishes in constant freezing water temperatures.”

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