Progress for First Malaria Vaccine

Following successful clinical trials, GlaxoSmithKline says it will submit its malaria vaccine for European regulatory approval.

By | October 8, 2013

WIKIMEDIA, CDC, RSABBATINILong-term clinical trial data on a malaria vaccine announced today (October 8) show that, although the efficacy of the immunization fades over time, a substantial proportion of children can be protected from infection. The RTS,S vaccine, backed by the PATH Malaria Vaccine Initiative and the Bill and Melinda Gates Foundation, cut the number of malaria cases by nearly half in babies 5 to 17 months old. The infection rate among vaccinated newborns, 6 to 12 weeks old, was also reduced by about 27 percent. The vaccine maker, GlaxoSmithKline (GSK), has said that it will move ahead with seeking regulatory approval from the European Medicines Agency in 2014.

“It appears that the RTS,S candidate vaccine has the potential to have a significant public health impact,” Halidou Tinto, principal investigator from the Nanoro, Burkina Faso, trial site and chair of the Clinical Trials Partnership Committee (CTPC), which oversees the RTS,S Phase 3 program, said in a press release.

If successful in its attempts to get approval, GSK's vaccine would be the first available to help prevent a disease that kills 660,000 people each year. The vaccine does have its faults, however—namely, that efficacy appears to fade over time and only a minority of children appears to be protected.

According to The Guardian, “GSK says the vaccine will be not-for-profit—but it will add 5 percent to the cost price which will go towards further research and development work on tropical diseases.” Nevertheless, Eleanor Riley, a professor of immunology at the London School of Hygiene and Tropical Medicine, points out that economics could be a barrier. “This will only get used in low-income countries if the people who normally pay for these initiatives—NGOs and charitable foundations—do so,” she told The Telegraph.

 

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. UC Berkeley Receives CRISPR Patent in Europe
    Daily News UC Berkeley Receives CRISPR Patent in Europe

    The European Patent Office will grant patent rights over the use of CRISPR in all cell types to a University of California team, contrasting with a recent decision in the U.S.

  2. DNA Replication Errors Contribute to Cancer Risk
  3. Should Healthy People Have Their Exomes Sequenced?
    Daily News Should Healthy People Have Their Exomes Sequenced?

    With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

  4. Rethinking a Cancer Drug Target
    Daily News Rethinking a Cancer Drug Target

    The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

Business Birmingham