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Gut Microbes Gobble Cocoa

Commensal bacteria that populate the human gastrointestinal tract help digest dark chocolate, releasing anti-inflammatory compounds, researchers report.

By | March 19, 2014

FLICKR, CART-WHEELSMicrobes like Bifidobacterium and lactic acid bacteria that reside in the human gut “feast on chocolate,” said Louisiana State University’s Maria Moore, an undergraduate student who assisted on a research that examined the effects of dark chocolate on gut bacteria, in a statement released at the American Chemical Society’s annual meeting being held in Dallas, Texas, this week. “When you eat dark chocolate, [these bacteria] grow and ferment it, producing compounds that are anti-inflammatory,” Moore added.

In in vitro experiments meant to model the human digestive tract, LSU food scientist John Finley’s team tested three cocoa powders, subjecting the substances to anaerobic fermentation using human fecal bacteria. The researchers found that, within the mock gut, the cocoa’s fiber content “is fermented and the large polyphenolic polymers are metabolized to smaller molecules, which are more easily absorbed,” Finley said in the statement. They also found that the smaller molecules “exhibit anti-inflammatory activity.” And gut microbes could help reduce a person’s feeling of hunger after having digested cocoa. “The microbes break down the fiber into short fatty chain acids, which get absorbed and can have an effect on satiety,” Finley told NPR’s The Salt blog.

The researchers have yet to confirm their results in vivo and cautioned that the apparent benefits of consuming cocoa powder don’t extend to gobbling dark chocolate bars from the corner store. “Our results don’t translate to a Hershey bar,” Finley told NPR. The British Heart Foundation’s Christopher Allen told BBC News that even though heart-healthy compounds like flavanols are found in dark chocolate, these molecules “are often destroyed by processing, and by the time a chocolate bar lands on the supermarket shelf it will also contain added extras such as sugar and fat.”

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Avatar of: T S Raman

T S Raman

Posts: 26

March 19, 2014

These are in vitro experiments, said to be "meant to model the human digestive tract". But I wonder whether Bifidobacterium and lactic acid bacteria are present in signiicant numbers in the "digestve tract", i.e. in the stomach and in the small intestines. They certainly cannot exist in the stomach, and even if they did, cannot carry out fermentation. If they existed in the large intestine and colon, their metabolic products are unlikely to be absorbed into the human body. The environment in the small intestines is also not conducive to growth of microbes. In any case, Why did the scientists not try Escherichia coli, which the large intestines are teeming with? Also. what are the "smaller molecules" produced from "large polyphenolic polymers"? Have they been identified, shown to be capable of being absorbed into the blood stream, and to have anti-infammatory activity?

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