Drug Produced in GM Chicken Approved

The US Food and Drug Administration greenlights a rare-disease drug that is produced in the eggs of genetically modified chickens.

By | December 10, 2015

FLICKR, DAVID GOEHRINGAlexion Pharmaceuticals’s Kanuma (sebelipase alfa), a recombinant human enzyme that replaces a faulty enzyme in patients with lysosomal acid lipase deficiency who are unable to break down fatty molecules, joins a handful of other “farmaceuticals”—drugs produced in genetically engineered, or genetically modified (GM), animals—that have hit the market in the last several years.

US Food and Drug Administration (FDA) approval of the GM chicken for the production of Kanuma “shows that the ATryn goats weren’t just a one-off,” says Jay Cormier, a lawyer at Hyman, Phelps and McNamara in Washington, DC, and a former scientific reviewer for the FDA, told Nature, referring to GM goats approved by the agency in 2009 for the production of an anticoagulant called ATryn (antithrombin) in their milk. “The process can function for more than just one particular unique case.” The FDA also approved a drug produced in transgenic rabbits last year.

In addition to evaluating the chicken-produced Kanuma for its efficacy and safety in humans, the FDA assessed whether the modifications to the chickens’ DNA would harm them, and whether the DNA edits were stable over generations. The FDA also made sure that the GM chickens are not likely to be mistakenly mixed with the food supply or pose significant environmental risks.

Purdue University geneticist William Muir said this approval is likely just the beginning. “The floodgates are opening,” he told Nature, “and I can’t wait to see what comes next.”

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Comments

Avatar of: vm123456

vm123456

Posts: 61

December 11, 2015

more people cured!

Popular Now

  1. Publishers’ Legal Action Advances Against Sci-Hub
  2. How Microbes May Influence Our Behavior
  3. Metabolomics Data Under Scrutiny
    Daily News Metabolomics Data Under Scrutiny

    Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.

  4. Sexual Touch Promotes Early Puberty
    Daily News Sexual Touch Promotes Early Puberty

    The brains and bodies of young female rats can be accelerated into puberty by the presence of an older male or by stimulation of the genitals.

AAAS