Ciliates Are Genetic-Code Deviants

Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.

By | October 1, 2016

© KIMBERLY BATTISTA

STOP AND GO SIGNALS

Certain ciliates use traditional stop codons ambiguously during translation. Sometimes these three-base-long RNA sequences code for an amino acid (green, left), and sometimes induce translation termination (red, right). Researchers propose that at the end of the mRNA coding sequence, the ribosome bumps up against proteins involved in termination—namely, eukaryotic release factors (eRF1 and eRF3) and poly(A) binding proteins (PABP)—thereby indicating that a stop codon means stop.

Read the full story.

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. Publishers’ Legal Action Advances Against Sci-Hub
  2. Metabolomics Data Under Scrutiny
    Daily News Metabolomics Data Under Scrutiny

    Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.

  3. How Microbes May Influence Our Behavior
  4. Do Microbes Trigger Alzheimer’s Disease?
AAAS