Drosophila, the winged workhorse of biology, has reached another milestone. Recently several labs have recorded electrophysiological data from the fly's central nervous system (CNS) neurons. "Drosophila is one of the most powerful neurobiological model systems around. The only thing it lacked was direct access to neurons of the CNS," says Leslie Griffith of Brandeis University, Waltham, Mass., where she has been recording from both larval and adult intact central nervous systems.[1] "I think that it was time for this technical barrier to fall."