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Concocting a Knock-Out Punch for HIV-1
Investigators probe RNA interference as a possible therapeutic strategy against HIV-1 infection
The Scientist 2004, 18(6):28
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Since the technique hit lab benches across the world researchers have assessed the specificity and power of gene silencing through RNA interference. RNAi has found use both as a research tool and as a potential therapeutic agent. In RNAi, an enzyme called Dicer processes long, double-stranded RNA (dsRNA) transcripts into smaller (21–25 nucleotide) dsRNAs, which target homologous messenger RNAs for degradation.
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