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Dscam Reveals its Bountiful Plan
The Scientist 2004, 18(12):14
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I got this cDNA sequence alignment for the Dscam gene in October 1999 while working in Larry Zipursky's lab. The gap in the alignment hinted at alternative splicing of the transmembrane domain. But that was just the tip of the iceberg: The handwritten inset is from my notes indicating not only this successful sequencing reaction but also that two reactions failed – much to my frustration (see the question marks). It turned out, however, that this was good news.
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