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Meiosis Models Face Tough Scrutiny
Venerable theories don't get a Holliday [sic] pass
The Scientist 2004, 18(14):24
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Thousands of geneticists owe their livelihoods to meiotic recombination, that diversity-promoting process during egg and sperm development when homologous chromosomes from Mom and Dad swap pieces. But recombination is so dauntingly complex that only a few geneticists have dared to propose models describing its underlying mechanics. For decades, cytology and genetic analysis provided data to test these hypotheses. Now molecular and biochemical tools are being applied as well.
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