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Genome-Scale Model Predicts Gene Regulation
UCSD team applies computational algorithm to transcriptional regulation in E. coli
The Scientist 2004, 18(14):42
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Most people like their predictions to pan out, but Markus Covert is glad when his fail. That's because he has developed a genome-scale mathematical model of the transcriptional interactions that regulate bacterial metabolism. The model's mistakes lead to new ideas about how the network is put together.
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