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Laying Down the Chips
The Scientist 2004, 18(15):38
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Looking to improve the quality of tools for discovering genomic regulatory regions, researchers at the National Institutes of Health combined Chromatin immunoprecipitation (ChIP) of hyper-acetylated histones, with serial analysis of gene expression (SAGE) technology. The process that they call genome-wide mapping technique (GMAT) could provide an alternative to ChIP-on-a-Chip techniques.[1]
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