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Seeds of a Micro Revolution
Plant studies reveal a slew of miRNAs and some real surprises Nicole Johnston
The Scientist 2004, 18(17):16
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Among structural and regulatory RNAs, the newest kids on the block have sparked a flurry of breakthrough discoveries in just three years. Tiny RNAs, called microRNAs (miRNAs), roughly 22 nucleotides long, are processed from stem-loop transcripts and bind and direct the repression of target mRNAs. Though both short interfering RNAs (siRNAs) and miRNAs are processed from double-stranded precursor transcripts by the Dicer nuclease, other events appear to diverge.
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