The Scientist : Seeds of a Micro Revolution [13/9/2004]

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by Nicole Johnston

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Seeds of a Micro Revolution

Plant studies reveal a slew of miRNAs and some real surprises Nicole Johnston

The Scientist 2004, 18(17):16

Published

13 September 2004

Among structural and regulatory RNAs, the newest kids on the block have sparked a flurry of breakthrough discoveries in just three years. Tiny RNAs, called microRNAs (miRNAs), roughly 22 nucleotides long, are processed from stem-loop transcripts and bind and direct the repression of target mRNAs. Though both short interfering RNAs (siRNAs) and miRNAs are processed from double-stranded precursor transcripts by the Dicer nuclease, other events appear to diverge.

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