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Discovering the 21st Amino Acid ... Again?
The Scientist 2004, 18(19):22
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Pyrrolysine, the 22nd amino acid, discovered in 2002, might lay claim to being the 21st following the discovery by Ohio State University researchers that, like the twenty canonical amino acids, it is translated by the genetic code using a natural tRNA synthetase-tRNA pair.[1]
Pyrrolysine is the first new amino acid discovered since selenocysteine in 1986, but the latter results from modification of serine after attachment to its tRNA.
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