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Wiser Gene Annotations with 5' SAGE?
The Scientist 2004, 18(20):46
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Serial analysis of gene expression (SAGE) has been used extensively to map and quantify transcripts in different tissues. But the technique, which extracts short oligos (14–21 bp long) from the 3' ends of pooled mRNAs, offers no insight into transcription start points. Three recent papers describe SAGE variants that can.
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