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Inclusion Bodies Acquitted
The Scientist 2004, 18(21):22
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Inclusion bodies play a protective, not pathogenic, role in Huntington disease, according to a recent study by Steven Finkbeiner of the Gladstone Institute of Neurological Disease at the University of California, San Francisco.[1]
The paper contributes to an ongoing debate about the role of inclusion bodies – intracellular clumps of mutant huntingtin (Htt) protein – in the pathology of diseases such as Huntington and spinocerebellar ataxia.
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