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Transcription by Design
Scientists use zinc fingers and small molecules to design artificial transcription regulators
The Scientist 2004, 18(21):30
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Scientists have long understood that changes in gene expression can lead to disease. But the details of the relationship between these changes and the diseases themselves remain sketchy. "What we'd like to have are molecules that control gene expression that we could use to probe those relationships," says Anna Mapp, a chemist at University of Michigan in Ann Arbor.
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