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Think Big, Dress Casual
Mike Snyder's recipe for success has helped shape functional genomics
The Scientist 2004, 18(21):55
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"We couldn't get that project funded for the life of us," says Yale University's Mike Snyder of the experiment that, in his opinion, launched the functional genomics era. It was the late 1980s, years before the dawn of DNA microarrays, and Snyder and his colleagues were proposing to use epitope-bearing transposons to tag every protein in yeast. With this collection, the scientists planned to track the positions of all 6,000 yeast proteins, information that would give them a handle on the proteins' potential functions.
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