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The Meselson-Stahl Experiment Lives On
In the age of stem cells, the immortal-strand hypothesis continues
The Scientist 2004, 18(22):56
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Matthew Meselson and Franklin Stahl's 1957 demonstration of DNA replication is considered "the most beautiful experiment in biology." Their density-shift demonstrations not only have stood the test of time, but also have renewed relevance for stem cell biology.
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