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Squeezing Out More Gene-Expression Data
Tangerine whole-genome profiling system challenges microarray supremacy
The Scientist 2004, 18(23):37
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In the world of gene-expression profiling, microarrays reign, but they are not without drawbacks. Microarrays have trouble with low-abundance transcripts and unidentified genes, for instance. So-called open systems, such as differential display and serial analysis of gene expression, don't require prior sequence knowledge, but they also either lack sensitivity or aren't quantitative, says Sten Linnarsson of Global Genomics in Stockholm.
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