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Cytogeneticists Embrace Molecular Karyotyping
Array-based techniques highlight chromosomal variations at the molecular level
The Scientist 2005, 19(1):33
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For decades, cytogeneticists have pored over images of metaphase chromosomes from tumors, noting the many gross aberrations these karyotypes can reveal. As classical techniques give way to fluorescence in situ hybridization (FISH), identifying genes affected in these chromosomal aberrations will likely offer clues to tumor progression.
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